Olga Alda Álvarez: The mechanisms behind stress. From populations to genes in nematodes

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8 sep 2006 13:30
Onderdeel: Wageningen UR
Locatie: Aula, gebouw 362, Gen. Foulkesweg 1, Wageningen
Organisatie: Wageningen Universiteit
Promotor: prof.dr.ir. J. Bakker (Nematologie ihb fysiologie en moleculaire ecologie van nematoden)
Co-Promotor: Dr.ir. J.E. Kammenga

 The pressure of abiotic stress factors on ecosystems has become a major societal and scientific concern over the past few decades. The growing awareness of the detrimental effects that processes such as climatic change or chemical contamination can have on ecosystems and the species that inhabit them has been the driving force of research that focuses on environmental risk assessment. Current risk assessment approaches are often based on naive and descriptive models, disregarding to a great extent the underlying mechanisms of stress response. In this thesis I have addressed the need for a fundamental understanding of stress response mechanisms in order to develop new rationales for risk assessment procedures. I focus on the mechanisms underlying the effect of different abiotic stress factors such as those imposed by toxic compounds and temperature changes on various species of nematodes. The study cross cuts through a range of different organizational levels; from the level of populations, to the most basic level of gene expression where the initial stress response takes place.
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