D. Pino Del Carpio: The genetics of the metabolome in Brassica rapa

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4 okt 2010 13:30 - 4 okt 2010 15:00
Onderdeel: Wageningen University
Locatie: Aula, gebouw 362, Gen. Foulkesweg 1, Wageningen
Organisatie: Wageningen University
Promotor: prof.dr. R.G.F. Visser (Pers. hgl. bij het lab. voor Plantenveredeling)
Co-Promotor: dr ir AB Bonnema

 In this thesis the metabolic variation in Brassica rapa is described based on results of metabolic profiling of a core collection of 168 accessions representing the different crop types and geographical origin and a Doubled Haploid population. We describe the genetic and phenotypic variation of this core collection to explore the possibility of following association mapping methods to identify genes involved in metabolic regulation. We explored through a genome wide and candidate gene approach different association mapping methods in a core collection and we combined the QTL analysis of targeted and untargeted metabolites profiled through LC-MS with the expression QTLs following a genetical genomics approach aiming to detect regulatory genes underlying the metabolite QTL.
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