Cell Biology and Immunology (CBI) : Immunomodulation for Sustainable Animal Production

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19 May 2003 - 23 May 2003
Unit: Wageningen University
Location: Conferentieoord De Wageningse Berg, Gen. Foulkesweg 96, Wageningen
Organisation: Arun Mishra, tel. 0317 485971, e-mail isap@wur.nl

Principles and uses of herbal and mushroom extracts. Developments in clinical and experimental immunology strongly suggest that many infectious diseases in animals arise because of stressful environmental conditions associated with suppression of the natural resistance and the innate immune system. The newborns of domestic food animals are virgin for 2-3 weeks and are highly susceptible for infections. In pigs the gut associated lymphoid tissue develops and matures during first month of life. Mature alveolar macrophages appear on 2 weeks of age, while NK cell activity requires 2-3 weeks in pigs. During this period, use of vaccines in disease prevention is very limited despite the fact that vaccines are the preferred method of disease prevention. When, however, a variety of infections agents contribute to the pathogenesis of a particular disease or when the impact of agent is apparently determined by stressful environmental conditions, non-specific stimulators of the innate natural resistance and capacity to induce adaptive immune responses such as herbal immunomodulators can offer advantages over current prophylactic and therapeutic approaches.
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