Ir. C. Schrooten : Genomic Variation in Dairy Cattle. Identification and Use

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27 Feb 2004 13:30
Unit: Wageningen University
Location: Aula (gebouw 362), Gen. Foulkesweg 1, Wageningen
Promotor: prof.dr.ir. J.A.M van Arendonk (Animal Breeding and Genetics)
Co Promotor: dr. ir. H. Bovenhuis

 The aim of breeding programs is to improve the genetic level for traits of economic interest, by selection based on phenotypic and pedigree information. Quantitative trait loci (QTL, regions of the genome influencing a particular trait) can be used as an additional information source. The aim of this thesis was to identify QTL in dairy cattle, and to study the effects of selection on QTL-information, for genetic progress and design of the breeding program.
First, an overview is given of the main QTL that have already been identified for milk production traits. Subsequently, results from a study to detect QTL affecting conformation traits and functional traits are reported. Besides, a method was developed to identify chromosomal regions affecting multiple traits. This method was applied to data on milk production, udder conformation, udder health and fertility traits. Finally, a number of multi-stage dairy cattle breeding schemes was studied, where the amount of variation explained by the QTL, and the level of preselection on QTL-information was varied.
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