Ms. A.M. (Agata) Brzozowska: New coatings for reducing protein adsorption

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29 Jun 2010 13:30
Unit: Laboratory of Physical Chemistry and Colloid Science
Location: Aula, building 362, Gen. Foulkesweg 1, Wageningen
Organisation: Wageningen University
Promotor: prof.dr. M.A. Cohen Stuart (Physical Chemistry and Colloid Chemistry)
Promotor: Prof.dr.ir. W. Norde
Co Promotor: Dr. A. de Keizer

 We studied the application of polymeric micelles as surface coatings that can
prevent accommodation of (bio-)organic matter at surfaces (biofouling). Protein
adsorption plays an important role, in particular during the initial stage of the
fouling process. We found out that micelles formed with oppositely charged
copolymers with neutral blocks adsorb on various surfaces forming a so-called
“polymer brush” that protect the surface from protein adsorption. The composition
of the micelles can be modified to match the properties of the surface in order to
obtain the best results. We have also studied the effect of flow on the micellar
coatings and their permeability in relation to potential application in industrial
membrane systems.
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